Benefits of NR

As the most efficient and effective NAD+ booster, NR can deliver results in a number of different areas:


  • Promotes healthy mitochondrial function, which is an important component of human aging1,3
  • Supplementation of an NAD+ precursor for one week in aged mice reversed their mitochondrial dysfunction and returned mitochondrial health and key biochemical markers of muscle health to levels similar to a young mouse1,2,3
  • Increases sirtuin activation, improving mitochondrial activity to help prevent cellular damage due to free radicals1,3


  • Shown to lower high-fat-diet-induced weight gain by enhancing energy metabolism1,2
Cardiovascular Health

Cardiovascular Health1

  • Promotes beneficial effects on blood lipids by maintaining healthy cholesterol levels already within normal range1


  • Maintains neuronal health1
  • Improves cognitive function and protects against axonal degeneration associated with aging1,2,3
“We obtained convincing evidence that oral supplementation of NR boosts NAD+ and enhances the body’s utilization of NAD+ to a greater degree than the conventional forms of vitamin B3. NR is the most efficient means to boost NAD+.”
Charles Brenner, PhD.

Charles Brenner, PhD.

Roy J. Carver, Chair and Head of Biochemistry; University of Iowa; The discoverer of NR as a vitamin, Dr. Brenner is the world's leading expert on NAD+ metabolism. He has published more than 35 articles in scientific literature on actions of NR and NAD+ metabolism.
  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
  2. Demonstrated in animal in-vitro studies.
  3. Demonstrated in an in-vivo mouse study.
  4. Trammell, S. A., Schmidt, M. S., Weidemann, B. J., Redpath, P., Jaksch, F., Dellinger, R. W., . . . Brenner, C. (2016). Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nature Communications, 7, 12948. doi:10.1038/ncomms12948